If you’ve heard about PRP therapy and wondered whether there’s something even more advanced — you’re not the only one. At Nevada Spine & Disc in Las Vegas, we offer PRF (Platelet-Rich Fibrin) — a next-generation regenerative therapy that uses a unique fibrin scaffold to release healing growth factors slowly and continuously, supporting longer-lasting tissue repair than first-generation PRP.
For chronic joint pain, disc issues, tendon injuries, and stubborn back pain, PRF can be the difference between a fast burst of healing and a sustained, weeks-long regenerative response. Here’s everything you need to know.
PRP and PRF are both made from your own blood — but they don’t behave the same way once they’re injected.
PRP is processed at higher centrifuge speeds and contains concentrated platelets without a structural matrix. When injected, PRP releases its growth factors in a rapid burst within minutes to hours — strong initial healing signal, but the window closes quickly.
PRF is processed at slower centrifuge speeds and contains platelets, leukocytes, and a natural fibrin matrix. Fibrin is the protein scaffold your body already uses to form clots and frameworks for healing. In PRF, that scaffold acts as a time-release container — trapping growth factors and releasing them slowly and steadily over 7 to 14 days.
In simple terms: PRP is a flash of healing. PRF is a slow, sustained release of healing. That extended release window matches how tissue actually rebuilds — which is why many patients see longer-lasting relief, especially in cases of chronic or degenerative conditions.
Platelet-Rich Fibrin is an autologous biologic — meaning it’s made entirely from a small sample of your own blood. After a quick draw, the blood is spun in a centrifuge using a specific slower protocol that preserves a natural fibrin matrix along with concentrated platelets, leukocytes (white blood cells), and regenerative components.
The result is a biologic concentrate that does three things really well: it delivers growth factors, it holds them in place at the treatment site, and it releases them gradually over a period of days to support sustained tissue repair.
Total in-office time is typically 45 to 60 minutes.
PRF tends to outperform PRP in chronic, degenerative, and slow-healing conditions — the situations where the body needs a steady supply of repair signals over time rather than a single push.
PRF is especially well-suited for:
PRF is not recommended for patients with active infections, blood disorders, certain cancers, those on blood thinners that cannot safely be paused, or pregnant patients. Our doctors will help you make a safe, informed decision during your consultation.
Most patients experience mild soreness or warmth at the injection site for 1–3 days. Because the PRF matrix releases growth factors gradually, improvements often build slowly over the first 2–6 weeks.
Important: As with PRP, chiropractic adjustments and strenuous physical therapy are typically paused for 10–14 days after PRF, then carefully reintroduced. We coordinate the timing for you.
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Visit us at: 8665 S Eastern Ave #103, Las Vegas, NV 89123
Yes. PRF is autologous — made from your own blood — so there’s no risk of allergic reaction or disease transmission. Side effects are typically limited to mild soreness at the injection site.
If chronic pain has been your story — or if PRP gave you a glimpse of relief but didn’t fully solve the problem — PRF therapy may be the right next step. The fibrin scaffold doesn’t just deliver healing signals; it holds them in place and releases them over time, matching how your body actually repairs tissue.
At Nevada Spine & Disc in Las Vegas, our doctors will evaluate your condition, discuss whether PRF, PRP, HCTP, or a combination is the right path, and build a treatment plan that fits your goals, schedule, and budget.